Sunday, May 3, 2009

Swine Report

I’m not an expert in anything, just a collator of info, but when the info is collated, it paints a very interesting picture. In chronological order, here’s what I’ve found.

Executive Summary

1976: Swine influenza kills one person in the US, vaccine kills 25 and paralyses 500 people.

1977: Two flu virus subtypes are found circulating the world population. Before that year, it was believed that only one human subtype circulated each flu season.

2004: At request of World Health Organization (WHO), US Center for Disease Control (CDC), start work on producing a combination of the deadly avian H5N1 virus with the highly transmittable human H3N2 virus. Apparently, WHO wants to develop evidence for warnings of pandemic doom. WTF?

2005: H5N1 infected swine found in Surabaya Indonesia. Although the virus genes were sequenced they were never publicly released and it was suspected WHO withheld them in their private database. The only human H5N1 sequence from Indonesia published at the time showed a novel HA cleavage site, it is common to find novel sequences in swine H5N1.

2009, Feb: A contaminated product mix of H3N2 and live H5N1 escapes Baxter International laboratory in Austria.

2009, Jan – March (financial first quarter): British and Japanese governments stockpile Relenza.

2009, April: First cases of human swine influenza detected in Mexico and the US. CDC states (April 23) testing of infections in the US shows the virus contains North American swine influenza, North American avian influenza, human influenza and Asian/European swine influenza.

It is reported that the isolates of influenza virus obtained in the outbreak have proven to be resistant to the adamantane antivirals, but susceptible to oseltamivir (Tamiflu) and zanamivir (Relenza).

2009, April 30: Researchers are perplexed on two fronts;
  1. Why are viral RNA sequences for all affected US states now published, while no info is forth coming from Mexico where out break preceded the US by weeks?
  2. Published info for US now omits any reference to avian influenza.
2009, May 1: It appears we may never know why the swine flu proved exclusively deadly to Mexicans as viral RNA sequences from that country continues to be withheld; meanwhile deposited (published) isolates from other countries amass unabated.

Main Report

Dr. Russell Blaylock:
"I was in the military during the first swine flu scare in 1976."

"At the time it became policy that all soldiers would be vaccinated for swine flu. As a medical officer I refused and almost faced a court martial, but the military didn’t want the bad publicity. Despite the assurance by all the experts in virology, including Dr. Sabin, the epidemic never materialized."

"What did materialize were 500 cases of Gullian-Barre paralysis, including 25 deaths—not due to the swine flu itself, but as a direct result of the vaccine. At the time President Gerald Ford, on advice from the CDC, called for vaccination of the entire population of the United States." link

Paralysis and death? Many vaccines for influenza variants contain not only the flu virus itself but also such yummy ingredients as; Chick embryos, Formaldehyde (used to preserve the dead), Triton X-100 (may contain peroxides) and Thimerosal (by weight, 50% mercury, one of the most deadly substances known to humans). link

Ron Paul also consolidates Dr Blaylock’s accounts. link

General info on Human Influenza:
Influenza viruses of two subtypes, H1N1 and H3N2, have been causing respiratory infections in humans since 1977. Before that year, it was believed that only one human subtype circulated each flu season. How did this unusual situation come about?

Major changes in the surface glycoproteins of influenza virus - called antigenic shift - lead to worldwide epidemics of influenza known as pandemics. There have been six instances of antigenic shift since 1889. In that year, H2N2 viruses circulated, followed by H3N8 in 1900, H1N1 in 1918, H2N2 in 1957, H3N2 in 1968, and H1N1 in 1977. Each pandemic strain carries HA and NA proteins that have been absent in humans for many years, and therefore immunity is either very low or nonexistent.

Influenza viruses of the H3N2 subtype were still circulating in humans in May of 1977 when H1N1 viruses were isolated in China and then Russia. Comparing viral RNA of one 1977 H1N1 isolate, with RNA from a virus isolated in 1950, found to researcher’s surprise, the two were closely related.

Why were the two viral genomes so similar? If the H1N1 viruses had been replicating in an animal host for 27 years, far more genetic differences would have been identified.

The authors suggested several possibilities, but only one is compelling:

The virus was frozen in a laboratory freezer since 1950, and was released, either by intent or accident, in 1977. This possibility has been denied by Chinese and Russian scientists, but remains to this day the only scientifically plausible explanation. link

A Plan for Pandemic
Jan 14, 2004

One of the worst fears of infectious disease experts is that the H5N1 avian influenza virus now circulating in parts of Asia will combine with a human-adapted flu virus to create a deadly new flu virus that could spread around the world.

Showing little ability to spread from person to person, a fear is that a hybrid could combine the killing power of the avian virus with the transmissibility of human flu viruses.

Now, rather than waiting to see if nature spawns such a hybrid, US scientists are planning to try to breed one themselves—in the name of preparedness.

The Centers for Disease Control and Prevention (CDC) will soon launch experiments designed to combine the H5N1 virus and human flu viruses and then see how the resulting hybrids affect animals. The goal is to assess the chances that such a "reassortant" virus will emerge and how dangerous it might be.

One plan is to infect cells in a laboratory tissue culture with avian (H5N1) and human (H3N2). Any viable viruses that emerge from this process will be seeded into animals that are considered good models for testing how flu viruses behave in humans.

The World Health Organization (WHO) has been "pleading" for laboratories to do this research, because it could provide some evidence to back up the agency's warnings about the risk of a flu pandemic. link

Editor’s note:

I wish I had known about this earlier, I would have given the scientists my free advice saving them years of effort and expense.

Q: What are the chances of such a virus emerging?
A: Fuck all, if you don’t make it emerge.

Q: How dangerous might it be?
A: Fucking dangerous.

Note: Pigs are good hosts for influenza viruses because their respiratory tract can be infected with both human and avian influenza viruses (as well as swine flu of course).

When two influenza viruses infect a cell, the viral genes mix and the new viruses produced can have genes from both infecting viruses. link

Swine to Human H5N1Transmission in Indonesia?
Thursday, May 18, 2006

Among the confirmed deaths on Wednesday was a 38-year-old catering businesswoman from Surabaya who had dealt with live pigs and pork meat before she died last week.

The above comments on a confirmed death in Surabaya are cause for concern. Last year H5N1 infected swine were identified in Surabaya. Reports indicated that all eight genes had been sequenced in Japan, and the sequence included a polybasic cleavage site. Although the sequence was generated over a year ago, it has not been made public via deposition at the public database at GenBank or Los Alamos. Instead it is almost certainly being withheld in the WHO private database.

Only one human H5N1 sequence has been deposited from Indonesia. That sequences has a novel HA cleavage site which is not found in any sequence at GenBank. However, a recent report suggested that the novel sequence was in human isolates from Indonesia as well as a cat isolate from Indonesia.

Novel sequences are common in swine H5N1, in part because there are a limited number of such sequences. link

27th February 2009
Baxter International confirms contaminated flu virus material was released from its plant in Austria.

The contaminated product, a mix of H3N2 seasonal flu viruses and unlabelled live H5N1 avian viruses, was supplied to an Austrian research company. The Austrian firm, Avir Green Hills Biotechnology, then sent portions of it to sub-contractors in the Czech Republic, Slovenia and Germany.

The contamination incident came to light when the subcontractor in the Czech Republic inoculated ferrets with the product and they died. Ferrets shouldn’t die from exposure to human H3N2 flu viruses. link

The first known cases of human swine flu infection in the US – 2009, were found around San Diego and San Antonio, cities that are 3000 kilometers apart. Except for a family pairing and two school mates, there appeared to be no links among the cases.
Editor’s note: Strange indeed given that contact (linking), is a pre requisite for the spread of viral infection.
Initial data from genetic sequencing revealed a seemingly unique influenza A virus of the H1N1 subtype made up of a distinctive mix of swine, bird and human flu virus genes. There have been no reports of this virus in pigs, said Dr. Marie Gramer, a swine flu expert with the University of Minnesota's college of veterinary medicine. "It doesn't seem to be very similar to anything that is currently circulating, from what I have," said Gramer, who has an extensive library of swine flu virus isolates. link

The isolates of influenza virus obtained in the current global outbreak have proven to be resistant to the adamantane antivirals, but susceptible to oseltamivir (Tamiflu) and zanamivir (Relenza). link

During the first three months of 2009 (first quarter), before swine flu infections were detected, the British and Japanese governments began stockpiling Relenza. As a result, sales of the inhalant antiviral in the first quarter, surpassed the entire previous year by four times. Biota Holdings, the licensing partner for Relenza, had a sharp rise in their share price just before the miraculous sales figures were made public. link

30 April 2009

Sequences of viral RNAs from 20 swine flu isolates have now been posted on the NCBI website. Included are isolates from California, Texas, New York, Ohio, Kansas, and Germany.

It is difficult to understand why RNA sequences of none of the Mexican isolates have been posted, which would enable us to determine if the viruses in that country are different from the others.
Editor’s note: “difficult to understand” wouldn’t be my words, deeply suspicious, might be appropriate.
CDC: “…the HA, PB2, PB1, PA, NP, NS genes contain gene segments from influenza viruses isolated from swine in North America, while the NA and M genes are most closely related to corresponding genes from influenza viruses isolated in swine population in Eurasia.

It is curious that CDC originally asserted that the new swine influenza virus inherited genes from human, pig, and bird viruses. The sequence information now available indicates a very different origin for these viruses. link
Editor’s note: again “curious” doesn’t do justice.

1 May 2009
Viral RNA sequences from 12 new isolates were deposited at NCBI, bringing the total to 32. Conspicuously missing are sequences from Mexican isolates.

It’s still not clear why these sequences have not been released; clearly the work has been done. link


The CDC alleges that strains from Mexico and elsewhere are all “very, very similar”. So why were the Mexican sequences never released, if there was nothing to hide? Its past the point of no return now, after such a period of concealment (totally unique to Mexico only), even if they produce the info in future, it would have to be considered dubious.

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